In older clients, this is important to comprehend as polypharmacy is typical and will potentiate the potential risk of DDIs and ADRs. Therefore, concurrent consumption of CYP2D6 inhibitors or inducers could potentiate or block tramadol conversion into ODT and This may maximize or minimize efficacy/ADRs on the prescribed tramadol. https://hemalchem.com/product/o-dsmt/