There is no backbone sampling so I generally uncover RMSD into the crystal structure to be < 1.0. Rest actually will do explicit bb sampling Consequently provides a lower Vitality composition than my protocol but may introduce the improvements that you observed. I am pasting my regular options file below: https://https-fastrelx-com90077.theideasblog.com/27223846/the-smart-trick-of-บ-หร-ไฟฟ-า-that-no-one-is-discussing