Without a doubt, TERT phosphorylation is proven to be demanded for telomerase activation. b Result of BETi on telomere regulation. BETi compete with acetylated histones for the binding for the BRD4 bromodomains releasing BRD4 from quick telomere, destabilizing telomere safety elaborate Group and lowering Telomerase activity. The progressive shortening of https://jq-1-as-a-bet-inhibitor36802.thezenweb.com/the-jq-1-in-epigenetics-diaries-69907576