Vaccine "unnaturalness" (artificiality) is one of the major anti-vaccine arguments raised in public debate. Therefore. health communication should rebut unnaturalness arguments and be cautious when emphasizing human intervention (e. g. https://www.roneverhart.com/Gretsch-G5210T-P90-Electromatic-Jet-Two-90-Single-Cut-Electric-Guitar-w-Bigsby-Mako-p23063/